Operation Smile Awards and Honors
- 2002 - The Sheikh Hamdan Bin Rashid Al Maktoum Award for Medical Sciences - Volunteers in Humanitarian Services
- 2002 - Frank Annunzio Award in the Arts/Humanities/Humanitarian field from the Christopher Columbus Fellowship Foundation
- 2001 - Antonio Feltrinelli Prize for Exceptional Endeavors of Outstanding Moral and Humanitarian Value from the Accademia Nazionale dei Lincei, which represents the National Academy of Science in Italy
- 2001 - Eckerd 100 Honoree for 2001, Eckerd Salute to Women program
- 2001 - Common Wealth Award of Distinguished Service (Public Service)
- 2000 - American Medical Association's Pride in the Profession Award
- 2000 - Kaanib ng Bayan Award for contribution to Philippine progress and development at the Year 2000 Presidential Awards for Filipino Individuals and Organizations Overseas
- 2000 - Philippine American Foundation's Friendship Award
- 1999 - Kellog's Hannah Neil World of Children Award
- 1999 - Greatest Irish Americans of the Century, Irish American magazine
- 1999 - International Humanity Award, American Red Cross Overseas Association
- 1999 - National Jefferson Award from the American Institute for Public Service
- 1999 - Kiwanis World Service Medal from Kiwanis International Board of Trustees
- 1999 - Golden Plate Award from the American Academy of Achievement
- 1999 - Charity Executive of the Year from the National Federation of Nonprofits
- 1998 - Distinguished Service Award from the American Society of Plastic Surgeons
- 1998 - Spirit of Raoul Wallenberg Humanitarian Award by the American Swedish Historical Museum of Philadelphia
- 1998 - Ronald McDonald House of Charities Award of Excellence
- 1997 - Servants of Peace Award from the UN representative to the Vatican
- 1997 - U.S. Secretary of State Madeleine Albright visits Operation Smile Vietnam
- 1997 - U.S. Secretary of Health and Human Services Donna Shalala attends Operation Smile ceremony in Vietnam
- 1996 - Recipient of the first $1 million Conrad N. Hilton Humanitarian Prize for "...exemplary and significant contributions to ease human suffering."
- 1996 - National Caring Award
- 1996 - Vasco Nunez de Balboa Award, highest humanitarian award in Panama
- 1990 - President's Volunteer Action Award presented by President George Bush
- 1988 - Presidential Citation for Private Sector Initiatives
- 1988, 1999 - Audiences with Pope John Paul II
- 1988 - Liberia Presidential Medal of Honor
- Keys to the City Award for Service to Mankind from Manila, the Philippines and Manizalesm Colombia
